Before a helper T cell can trigger a response to a pathogen or parasite, it has to "feel" these molecular bits of an invader displayed on the surface of an antigen-presenting cell ( APC). 在辅助T细胞激发针对病原的免疫反应之前,它必须感觉到位于抗原递呈细胞面表的入侵者分子片段。
This review summarizes theory and method-ology of prediction for helper T cell epitopes, and their application in vaccine development against parasites, and new research directions are also discussed. 本文概述辅助T细胞表位预测的理论和方法及其在寄生虫疫苗研发中的应用,并讨论未来的研究方向。
The CD4+ test directly measures the abundance of the helper T cell, an of immune cell in the bloodstream distinguishable because they are the only ones that carry the CD4 marker. CD4+试验直接检测辅助型T细胞数量。辅助型T细胞是血流中可分辨的免疫细胞中的一种,因为只有他们才具有CD4标志物。
Antibody class switching declines significantly once helper T cell function fails. 抗体类别转换的跌幅明显一次辅助性T细胞的功能失败。
These effects are primarily due to the loss of any helper T cell that can interact with the B lymphocyte correctly. 这些影响主要是由于失去任何辅助性T细胞可以与B淋巴细胞正常。
Objective To review the relationship between T helper cell 1/ T helper cell 2 ( Th1/ Th2) shift and tumor recurrence. 目的探讨T辅助淋巴细胞Ⅰ型(Th1)/T辅助淋巴细胞Ⅱ型(Th2)在肿瘤复发中的研究进展。
Advances in the Experimental Study on the Role of Helper T Cell Subsets in the Pathogenesis and the Treatment of Autoimmune Diseases Th细胞亚群在自身免疫病的发病及治疗中作用的实验研究进展
Study on regularity of changes of helper T cell subgroup Th1/ Th2 and interference effect of traditional Chinese medicine in mice with acute hemorrhage necrotizing pancreatitis 急性出血坏死性胰腺炎小鼠辅助性T细胞亚群1/2的变化规律及中药干预作用研究
T helper cell ( CD4~+) and T suppress cell ( CD8~+) are important immune adjustment cells, which can strengthen or suppress the activation of other immune cells. T淋巴细胞亚群中的辅助性T细胞(CD4+)和抑制性T细胞(CD8+)是机体重要的免疫调节细胞,可增强或抑制其他免疫细胞的活性。
Study on Normal Pregnancy and Recurrent Spontaneous Abortions from Helper T Cell 1/ Helper T Cell 2 Cytokines Balance T辅助细胞1、2细胞因子平衡与正常妊娠及习惯性流产关系的初步探讨
Function of cytokines secreted by helper T cell subsets from maternal peripheral blood and para-embryo during early pregnancy 孕早期母体外周血及胚胎周围辅助T细胞亚群分泌功能
Compared to those of two nationalities, the helper T cell percentage and CD4/ CD8 ratio of Uygur male were lower than those in Han male. 维吾尔族与汉族男性在辅助性T细胞及CD4/CD8比值上的差异有统计学意义,前者略低于后者;
In this paper the functions of helper T ( Th) cell subsets, their cross regulation and agents affected their differentiation, as well as the role of Th subsets in the possible pathogenesis of autoimmune diseases were reviewed. 本文回顾了Th细胞亚群的功能、交互调节、影响其分化的因素以及Th细胞亚群在自身免疫病发病中的可能作用;
Conclusion Granulomatous slack skin disease is an indolent T helper cell lymphoma derived from either αβ T cell or γδ T cell. 结论:肉芽肿性松弛皮肤病是CD4+辅助性T细胞淋巴瘤的罕见类型。
Changes of AgNORs expression of T lymphocytes and helper T cell subsets in peripheral blood mononuclear cells from cancer patients 肿瘤病人T细胞核仁嗜银蛋白和辅助性T细胞亚群变化
Conclusion IL-12 actively played a part in inflammatory reaction and played an important role in the conversion of T helper cell to type I T helper cell ( TH1) and in mediating cellular immune process. 结论IL-12参与了炎症反应,并在T辅助细胞向I型T辅助细胞转化,介导细胞免疫过程中发挥重要作用。
Protein sequence analysis and helper T cell epitope prediction of keratin 17 人角蛋白17的序列分析及辅助性T细胞表位预测
At the resting state in the peripheral blood, CD26/ DPIV was preferentially expressed on the helper/ memory T cell population. 外周血中静止期的CD26/DPIV主要表达在记忆性辅助T细胞上。
This method can raise the helper T cell, while decrease the cytotoxic T cell at the same time selectivity, making the ratio of the two goes up, thus make the organism of virus infection keep a good immunity condition. 本法可在选择性升高辅助性T细胞CD4的同时抑制细胞毒T细胞CD8,使二者比值升高,从而使病毒入侵后的机体保持良好的免疫状态。
As a growth factor of T cells, IL-12 can stimulate the dentification of CD4~+ cells mediated by Th1 ( helper T cell) and regulate cellular immune responses. 作为T细胞的生长因子,IL-12能促进Th1介导的CD4~+细胞的分化和增殖,控制细胞免疫调节反应;
Objective To investigate the significance of helper T cell 1 ( Th1)/ Th2 cytokines unbalance in children with hepatitis B virus-associated glomerulonephritis ( HBV-GN). 目的探讨Th1/Th2细胞因子失衡在乙肝病毒相关性肾炎(HBV-GN)发病中的意义。
Currently, cyclosporin A ( CsA) is believed to be able to block the production of T helper cell growth factor interleukin 2 ( IL 2), to affect interaction of T cells and B cells, and inhibit clonal T cell expansion. 目前认为环孢霉素A(CsA)可以阻碍辅助T细胞生长因子白介素2(IL2)的生成,影响T、B细胞的相互作用,抑制克隆性T细胞的扩增。
Objective: We analyzed the protein sequence and predicted the helper T cell epitopes in order to lay the foundation for the immunological pathogenesis of psoriasis. 目的:本文对角蛋白17的序列和辅助性T细胞抗原表位进行了分析预测,为一定遗传背景下T细胞介导的自身免疫紊乱引发银屑病这一观点提供了研究基础。
Effect of Irradiation on T Cell, Helper T Cell and Suppressor T Cell by~ ( 60) Co γ-ray 用单克隆抗体研究~(60)Coγ线对培养后T细胞及其亚群的辐射效应
Helper T ( Th) cell is crucial in immunity for its interaction with other cells, especially regulating the immune function through secreted cytokines. However, the effects of ursolic acid on T helper cell are very poorly understood. 辅助性淋巴细胞(Th细胞)在机体的免疫中起着极为关键的作用,尤其是通过分泌细胞因子调节免疫功能,目前尚无熊果酸对Th细胞影响的报道。
Now research on multiple mediators of inflammation has revealed that normal lung is in a refined balance of inflammation and anti-inflammation. The two phenotypes of helper T cell just deputy above-mentioned balance. 目前对于多种炎症介质的研究揭示了正常肺组织处于促炎和抗炎反应的精细平衡中,而辅助性T细胞(HelperTcell,Th)的两种不同表型恰好代表了上述的平衡。